Neural response to emotional prosody in schizophrenia and in bipolar affective disorder

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Neural response to emotional prosody in schizophrenia and in bipolar affective disorder.

BACKGROUND Evidence suggests a reversal of the normal left-lateralised response to speech in schizophrenia. AIMS To test the brain's response to emotional prosody in schizophrenia and bipolar disorder. METHOD BOLD contrast functional magnetic resonance imaging of subjects while they passively listened or attended to sentences that differed in emotional prosody. RESULTS Patients with schiz...

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De novo CNVs in bipolar affective disorder and schizophrenia

An increased rate of de novo copy number variants (CNVs) has been found in schizophrenia (SZ), autism and developmental delay. An increased rate has also been reported in bipolar affective disorder (BD). Here, in a larger BD sample, we aimed to replicate these findings and compare de novo CNVs between SZ and BD. We used Illumina microarrays to genotype 368 BD probands, 76 SZ probands and all th...

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Schizophrenia and Bipolar Affective Disorder: a Dimensional Approach.

AIM Schizophrenia (SCH) and bipolar affective disorder (BAD) are currently classified separately according to the DSM (The Diagnostic and Statistical Manual of Mental Disorders) and ICD (International Statistical Classification of Diseases and Related Health Problems) standardized diagnostic guidelines. However, the validity of this categorical approach is controversial because psychotic sympto...

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Emotional response deficits in schizophrenia: insights from affective science.

Our understanding of the emotional features of schizophrenia has benefited greatly from the adoption of methods and theory from the field of affective science. This article covers basic concepts and methods from affective science on the psychological and neural mechanisms contributing to emotions and reviews the ways in which this research has advanced our understanding of emotional response de...

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[Disturbances of emotional prosody in schizophrenia].

Disturbances in understanding and expression of emotional prosody of speech (aprosodia) belong to frequent but rarely described symptoms of schizophrenia, that negatively influence the life quality of patients. The role of prosody in the process of verbal communication is to complement and emphasize the language (linguistic prosody) and affective (emotional prosody) aspects of the spoken announ...

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ژورنال

عنوان ژورنال: British Journal of Psychiatry

سال: 2004

ISSN: 0007-1250,1472-1465

DOI: 10.1192/bjp.184.3.223